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Brief Summary: This is a study to assess the safety and pharmacokinetics of weekly infusions of mg/kg of Prolastin-C (alpha1-proteinase inhibitor [. Choose a specific alpha1-proteinase inhibitor product: · Aralast NP · Glassia · Prolastin-C · Zemaira. Aetna considers alpha 1-proteinase inhibitor (e.g., Aralast NP, Glassia, Prolastin-C, and Zemaira) therapy medically necessary for the treatment of emphysema.

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In contrast to other plasma proteins, α1-PI is a proteinase inhibitor and thus able to resist degradation by digestive and bacterial proteinases (see Figure 1). The intent of the Alpha1-Proteinase Inhibitors drug policy is to ensure appropriate selection of patients for therapy based on product labeling, clinical. PROLASTIN®-C LIQUID is an alpha1-proteinase inhibitor (human) (alpha1-PI) indicated for chronic augmentation and maintenance therapy in adults with clinical.

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Brief Summary: This is a study to assess the safety and pharmacokinetics of weekly infusions of mg/kg of Prolastin-C (alpha1-proteinase inhibitor [. Choose a specific alpha1-proteinase inhibitor product: · Aralast NP · Glassia · Prolastin-C · Zemaira. Efficacy and Safety of Alpha1-Proteinase Inhibitor (Human), Modified Process (Alpha-1 MP) in Subjects With Pulmonary Emphysema Due to Alpha1 Antitrypsin.